L-methionine: Precursor to S-adenosylmethionine (SAMe) (1). SAMe is directly involved in methylation processes including catecholamine synthesis (2).
L-tyrosine: Precursor to catecholamines including dopamine, norepinephrine, and epinephrine.
L-histidine: Precursor to histamine. In the central nervous system, histamine plays an important role in the release of pituitary hormones and wakefulness (3).
Rhodiola rosea root extract (5% rosavins): Adaptogen that has been shown to reduce stress-induced effects (4,5).* In a randomized, double-blind, placebo-controlled study, Rhodiola rosea was shown to significantly reduce mental fatigue and improve general well-being under stress (5).*
Green tea leaf extract (Camellia sinensis) (65% EGCG): Epigallocatechin gallate (EGCG) is a polyphenol in green tea that provides antioxidant protection by its ability to scavenge free radicals and metal ions (6).* EGCG has been shown to increase resistance to fatigue in vivo(7).*
Vitamins B and C: Active forms of pantothenic acid, niacin, B6, folate, B12, and C are important for the synthesis of adrenal hormones and neurotransmitters (8-12).*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.